PharmaDB
Use case · Supplier Discovery & Qualification · Geographic Origin Diversification v.04.2026 · refreshed weekly
Use cases Supplier Discovery & Qualification Geographic Origin Diversification
Supplier Discovery & Qualification Buyer view Data · trade flowsData · FDA Type II DMF register Live

Geographic Origin Diversification

Quantify how many countries supply your API. Origin country count, share of leading origin, and the share of supply concentrated outside the dominant origin.

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Example output · origin diversification across observable molecule-importer pairs
0.5% · Multi-origin share of (molecule, importer) pairs, 2024
n=8,084 (molecule, importer) pairs in 2024 Illustrative

Of 8,084 (molecule, importer) pairs visible in the 2024 trade record, 8,047 (99.5%) are served from a single origin country. Only 37 pairs (0.5%) draw from two or more origins. The trade graph is structurally single-origin at the working unit; diversification is the exception, not the baseline.

Single-origin pairs
8,047
99.5%
Multi-origin pairs (2+)
37
0.5%
Avg origins per pair
1.005
Most-diversified pair
9 origins
tamsulosin into CY
30 seconds

How it works

molecule losartan origin IN destination BR
01

Pick a molecule.

Type the INN. The AI agent pulls every export-origin country with observable shipments on the molecule, last two years.

0 HHI 0.42 1
computed · pre-joined · anonymised
02

The AI agent computes the spread.

Distinct origin countries, share of the leading origin, share outside the top origin. Normalised to a 0-to-1 single-origin score.

brief · cited
Lane concentration · structurally concentrated
HHI0.42
Top-3 share71%
Actionqualify second source
03

Save the diversification brief.

Citation-anchored brief with the origin breakdown, dominant-origin share trajectory, and a chip showing diversification grade.

Why a buyer runs it

Concentration risk above the lane, at the origin level.

Catch single-origin exposure.

A molecule sourced from one country is a different risk than a molecule sourced from three. Origin-level concentration sits above lane-level HHI and is often invisible until disruption hits.

Trajectory matters.

An origin moving from 95% to 99% share is a deteriorating signal even before any one supplier disrupts. The brief tracks share quarter on quarter.

Diversification grade chip.

Single-origin, dominant-origin, balanced, or distributed. The grade chip is the one-look signal on the catalog row.

Weekly refresh.

Trade aggregates refresh weekly. Origin share movement propagates on the next refresh.

What a real chat looks like

Type a molecule. The AI agent returns the geographic spread.

A real chat thread in PharmaDB. Type a question, the AI agent runs the tools, the answer lands as a saveable note.

Origin diversification · tirzepatide
chat · saved 2 min ago
You
How geographically diversified is the tirzepatide API supply? Origin country count, share of the leading origin, and the percentage of supply outside the top origin.
F
Running tool pharmagraph_query
molecule_country_flow · tirzepatide · 2024-2025 origin aggregate
F
Tirzepatide is single-origin in observable trade. India accounts for 100% of declared export value across 2024 and 2025, on $1.74M in customs-traced commerce. The cohort of 11 distinct Indian manufacturers is healthy at lane level, but the molecule carries origin-level concentration risk that lane HHI alone does not surface. The companion analysis is the lane substitution playbook.
Origin countries
1
Leading origin share
100%
Manufacturers
11
Global trade value
$1.74M
Cited molecule_country_flow tirzepatide 24-25 company_trade_exports_by_molecule 11 manufacturers api_docs 37 active DMFs
Ask a follow-up... ⌘ ↵
Time-to-answer

Manual workflow vs. PharmaDB.

Manual workflow
Excel · email · syndicated reports
  1. 01 Pull trade declarations across all origins 3-4 hr
  2. 02 Filter to molecule-matched shipments 1-2 hr
  3. 03 Aggregate by origin country 1 hr
  4. 04 Compute share, count manufacturers 2 hr
  5. 05 Track quarterly trajectory 2 hr
Total cycle time 1 day per molecule
PharmaDB
The AI agent · one query · cited
One query.
Pre-joined warehouse. Customs is matched to the molecule catalog and aggregated by origin. The AI agent returns the geographic spread with citation.
Total cycle time Under a minute
Run it across your portfolio

How concentrated origin supply is, per molecule.

Twenty molecules · dominant-origin share, latest two years · HHI proxy on the 0 to 1 single-origin scale.

Apixaban
global origins
0.62
Sitagliptin
global origins
0.75
Dapagliflozin
global origins
0.70
Empagliflozin
global origins
0.72
Valsartan
global origins
0.65
Ticagrelor
global origins
0.82
Telmisartan
global origins
0.80
Sacubitril
global origins
0.85
Linagliptin
global origins
0.83
Olmesartan
global origins
0.88
Palbociclib
global origins
0.90
Vortioxetine
global origins
0.92
Enzalutamide
global origins
0.92
Abiraterone
global origins
0.93
Edoxaban
global origins
0.95
Ibrutinib
global origins
0.95
Tofacitinib
global origins
0.96
Olaparib
global origins
0.97
Liraglutide
global origins
0.99
Tirzepatide
global origins
1.00
Competitive Monitored Concentrated Near-monopoly

Origin diversification is the above-the-lane view of supply concentration. PharmaDB joins trade aggregates to the molecule catalog and reports distinct origin countries plus dominant-origin share so single-origin exposure surfaces before disruption hits. The view rests on molecule_country_flow. Refresh cadence is weekly.

FAQ

Frequently asked

How is origin diversification different from lane HHI?+

Lane HHI measures concentration of exporters within a single origin-destination lane. Origin diversification measures concentration of countries supplying the molecule globally. A lane can look competitive at HHI 0.3 while the molecule remains single-origin (one country, many exporters).

Why does tirzepatide show as single-origin?+

The observable customs trace for tirzepatide API in 2024 and 2025 is 100% Indian-export. Other origins may have unreported flows or be supplying domestic markets that the trade feed does not capture. PharmaDB labels these gaps explicitly when the data confidence is partial.

India dominates many molecules — is the metric still useful?+

Yes, the spread within Indian dominance varies considerably. Some molecules show 60 percent India with meaningful supply from China, Italy, or Spain. Others show 99 percent India. The grade chip surfaces this gradation; lane HHI does not.

How does this connect to dual-sourcing strategy?+

A single-origin molecule needs a different dual-source strategy than a multi-origin one. The latter can dual-source within current supply geography; the former requires qualifying a supplier in a new country, which is a longer regulatory project.

Are intermediates and KSMs included?+

The headline metric is API-level. The companion analysis, China intermediate dependency map, surfaces upstream KSM exposure where Indian APIs depend on Chinese intermediates not visible in the API trade feed.

How fresh is the data?+

Weekly. Trade aggregates refresh weekly; origin share is recomputed on every refresh. The catalog row carries an as-of timestamp on every result page.

Run your question.

Bring the molecule, the lane, or the supplier you're sourcing this week. The AI agent runs it on PharmaDB in 30 minutes. You keep the brief.

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